Moisture analysis is a crucial aspect of various industries, including pharmaceuticals, food, and petrochemicals. It is a complex and often time-consuming procedure that can determine the moisture content of a substance accurately. Karl Fischer Titration (KFT) is a widely recognized technique that provides accurate moisture determination.
KFT involves reacting a sample with a Karl Fischer reagent, which consists of iodine, sulfur dioxide, and a base in a specific solvent. The reaction consumes water present in the sample, resulting in a color change from clear to yellowish-brown. The titration proceeds until there is no further water in the sample, indicated by a stable endpoint.
The endpoint is detected using a specific indicator solution or an electrochemical cell. The amount of Karl Fischer reagent used to reach the endpoint is proportional to the moisture content of the sample.
Performing KFT requires specialized equipment, including a titration vessel, burette, and a titrator. The Karl Fischer reagent is commercially available and must be stored in a dry environment to prevent contamination.
Karl Fischer Titration is a reliable and accurate technique for moisture determination. Its versatility and specificity make it suitable for various industries where moisture analysis is critical for quality control and product development.